Hotels in Defiance

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Check prices for these dates

Tonight
Jul 3 - Jul 4
Tomorrow
Jul 4 - Jul 5
This weekend
Jul 4 - Jul 6
Next weekend
Jul 11 - Jul 13

Where to stay in Defiance?

TownePlace Suites by Marriott St. Louis Chesterfield
Property amenity

TownePlace Suites by Marriott St. Louis Chesterfield

3.0 star property
8.8 out of 10, Excellent, (244)
$132 nightly
The price is $155
Jul 20 - Jul 21
Total includes taxes and fees
TownePlace Suites by Marriott St. Louis Chesterfield
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Defiance

August A. Busch Memorial Conservation Area

August A. Busch Memorial Conservation Area

If you like spending time outside, why not spend the afternoon at August A. Busch Memorial Conservation Area, a park located 30.2 mi (48.6 km) from the centre of St. Louis.

See properties in August A. Busch Memorial Conservation Area
August A. Busch Memorial Conservation Area

Learn more about Defiance

Defiance is well-known for its attractions such as Yellow Farmhouse Winery and Chandler Hill Vineyards.

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Check out the Defiance hotels guests love right now

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

10/10 Excellent
"It was great breakfast, pool and hot"
Anita 5-night trip
Posted 1 day ago
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Frequently asked questions

What hotels do travelers recommend in Defiance?
Guests like The Wildwood Hotel.
Can I book refundable accommodations in Defiance?
If you need the flexibility to change your plans to Defiance, most hotels offer refundable* rates you can book. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Defiance be like during my vacation?
July and August are typically the warmest months in Defiance when the average temp is 76°F. January and February are the coldest months when the average temperature is 38°F. May and April are the months with the most rain.
Why should I book my Defiance hotel through Hotels.com?
There are lots of reasons to book your Defiance trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Find out more about Defiance

Find out more about Defiance

If you're looking to discover somewhere new, look no further than Defiance. Whether you're planning to stay for a night or for the week, the area around Defiance has accommodations to fit every need. Search for hotels in Defiance with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Defiance hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Defiance hotel deals are here with our lowest price guarantee.