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Hotels in Defiance
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The Wildwood Hotel
The Wildwood Hotel
3.5 star property
Wildwood
9.2 out of 10, Wonderful, (1590)
9.2/10
Wonderful
(1590)
$95 nightly
The price is $111
$111 total
Oct 13 - Oct 14
Total with taxes and fees
Sleep Inn & Suites O'Fallon MO - Technology Drive
Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
O'Fallon
8.8 out of 10, Excellent, (1008)
8.8/10
Excellent
(1008)
$87 nightly
The price is $103
$103 total
Oct 14 - Oct 15
Total with taxes and fees
Holiday Inn Express & Suites St Peters by IHG
Holiday Inn Express & Suites St Peters by IHG
2.5 star property
St. Peters
9.2 out of 10, Wonderful, (354)
9.2/10
Wonderful
(354)
$100 nightly
The price is $115
$115 total
Oct 23 - Oct 24
Total with taxes and fees
LAKEVIEWINN
LAKEVIEWINN
2.5 star property
Lake St Louis
5.4 out of 10, (25)
5.4/10
(25)
$81 nightly
The price is $91
$91 total
Oct 11 - Oct 12
Total with taxes and fees
Hampton Inn St. Charles St. Peters
Hampton Inn St. Charles St. Peters
2.5 star property
St. Charles
8.0 out of 10, Very Good, (1006)
8.0/10
Very Good
(1006)
$98 nightly
The price is $112
$112 total
Oct 19 - Oct 20
Total with taxes and fees
Economy Inn Wentzville
Economy Inn Wentzville
2.0 star property
Wentzville
6.4 out of 10, (468)
6.4/10
(468)
$54 nightly
The price is $62
$62 total
Oct 12 - Oct 13
Total with taxes and fees
Quality Inn
Quality Inn
2.5 star property
Foristell
8.2 out of 10, Very Good, (867)
8.2/10
Very Good
(867)
$88 nightly
The price is $100
$100 total
Nov 9 - Nov 10
Total with taxes and fees
Holiday Inn Express & Suites Wentzville St Louis West by IHG
Holiday Inn Express & Suites Wentzville St Louis West by IHG
2.5 star property
Wentzville
9.4 out of 10, Exceptional, (803)
9.4/10
Exceptional
(803)
$131 nightly
The price is $156
$156 total
Nov 1 - Nov 2
Total with taxes and fees
Super 8 by Wyndham Eureka/Six Flags Nearby
Super 8 by Wyndham Eureka/Six Flags Nearby
2.0 star property
Eureka
7.0 out of 10, Good, (1005)
7.0/10
Good
(1005)
$60 nightly
The price is $70
$70 total
Oct 26 - Oct 27
Total with taxes and fees
Super 8 by Wyndham Warrenton
Super 8 by Wyndham Warrenton
2.0 star property
Warrenton
7.4 out of 10, Good, (602)
7.4/10
Good
(602)
$68 nightly
The price is $78
$78 total
Oct 19 - Oct 20
Total with taxes and fees
Super 8 by Wyndham Washington
Super 8 by Wyndham Washington
2.0 star property
Washington
8.4 out of 10, Very Good, (676)
8.4/10
Very Good
(676)
$87 nightly
The price is $100
$100 total
Oct 26 - Oct 27
Total with taxes and fees
Comfort Inn & Suites St. Louis - O'Fallon
Comfort Inn & Suites St. Louis - O'Fallon
2.5 star property
O'Fallon
7.6 out of 10, Good, (1005)
7.6/10
Good
(1005)
$77 nightly
The price is $90
$90 total
Oct 26 - Oct 27
Total with taxes and fees
Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
2.5 star property
Chesterfield
9.0 out of 10, Wonderful, (974)
9.0/10
Wonderful
(974)
$91 nightly
The price is $106
$106 total
Oct 31 - Nov 1
Total with taxes and fees
Holiday Inn Express St. Louis West - O'Fallon by IHG
Holiday Inn Express St. Louis West - O'Fallon by IHG
2.5 star property
O'Fallon
8.6 out of 10, Excellent, (795)
8.6/10
Excellent
(795)
$95 nightly
The price is $112
$112 total
Oct 19 - Oct 20
Total with taxes and fees
Best Western Plus Washington Hotel
Best Western Plus Washington Hotel
2.5 star property
Washington
9.0 out of 10, Wonderful, (608)
9.0/10
Wonderful
(608)
$129 nightly
The price is $147
$147 total
Oct 12 - Oct 13
Total with taxes and fees
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
Fenton
8.2 out of 10, Very Good, (1012)
8.2/10
Very Good
(1012)
$85 nightly
The price is $98
$98 total
Nov 2 - Nov 3
Total with taxes and fees
Super 8 by Wyndham Union
Super 8 by Wyndham Union
2.0 star property
Union
8.2 out of 10, Very Good, (621)
8.2/10
Very Good
(621)
$80 nightly
The price is $88
$88 total
Oct 19 - Oct 20
Total with taxes and fees
Hollywood Casino & Hotel St. Louis
Hollywood Casino & Hotel St. Louis
3.5 star property
Maryland Heights
8.4 out of 10, Very Good, (2162)
8.4/10
Very Good
(2162)
$100 nightly
The price is $117
$117 total
Oct 21 - Oct 22
Total with taxes and fees
Baymont by Wyndham Warrenton
Baymont by Wyndham Warrenton
2.5 star property
Warrenton
7.4 out of 10, Good, (1004)
7.4/10
Good
(1004)
$86 nightly
The price is $98
$98 total
Nov 2 - Nov 3
Total with taxes and fees
Super 8 by Wyndham St. Clair MO
Super 8 by Wyndham St. Clair MO
2.0 star property
St. Clair
7.2 out of 10, Good, (916)
7.2/10
Good
(916)
$67 nightly
The price is $73
$73 total
Oct 13 - Oct 14
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Defiance
Pet friendly
Family friendly
Cottage
Top landmarks in Defiance
Learn more about Defiance
Defiance is well-known for its attractions such as Yellow Farmhouse Winery and Chandler Hill Vineyards.
Check out reviews of Defiance hotels guests love
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
10/10 Excellent
"Friendly staff, clean facility!"
Sonesta ES Suites St. Louis - Chesterfield
10/10 Excellent
"This was a very nice place to stay. Centrally located, very clean and quiet with a great breakfast!"
Wingate by Wyndham St. Louis/Fenton Route 66
10/10 Excellent
"I was greeted by an extremely please and knowlegable lady at the front desk. She was super friendly and happy, and helpful with making sure you had directions to where you needed to go. The lobby was beautiful. My room was absolutely amazing!! It was hot outside and it was so nice walking into my room and the a/c on and the room cool!! The bed was nice and comfortable. I very much enjoyed having all the lighting in the room along with the outlets!! The only thing I will say is that in the bathroom there is large pieces of something falling down off the ceiling that needs to be repaired. It wasn't a big issue to me, but to some it may be. Other than that issue, my stay was very relaxing and comortable!!! I would most defintely recommend staying and when back in this area, I will be staying again!!!! Thank you for the great service I received."
Courtyard by Marriott St Louis Creve Coeur
10/10 Excellent
"Great Hotel"
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
10/10 Excellent
"Clean room and staff was great "
La Quinta Inn & Suites by Wyndham St. Louis Westport
10/10 Excellent
"Had stayed and kept car for 14 days there. Decided to spend another nite when back from vac. No issues. Nice place to stay"
Hampton Inn St. Charles St. Peters
10/10 Excellent
"Excellent hotel. Excellent location, friendly staff, and delicious breakfast."
The Wildwood Hotel
10/10 Excellent
"Visited to do some writing. Staff was friendly and helpful, all amenities were clean and functional. Wildwood area is pretty quiet after 8. "
Hollywood Casino & Hotel St. Louis
10/10 Excellent
"Clean & great location"
Frequently asked questions
How much does a hotel room cost in Defiance?
You can discover great hotels in Defiance from $62 with properties to suit all budgets and needs. If you're looking for an affordable hotel in Defiance that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com. If you're a member, don't forget to sign in to your account to unlock more savings.
How can I find deals and earn rewards at Defiance hotels?
Members can save up to 20% on select hotels in Defiance. Plus, Silver, Gold and Platinum members earn extra rewards on VIP Access bookings, making each stay even more rewarding.
Can I book Defiance hotels with free cancellation?
To book a refundable Defiance hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
Are all taxes and fees included in the Defiance hotel prices shown on Hotels.com?
Hotels.com provides upfront pricing so you can relax knowing you won't be met with surprise additional fees or taxes when you're ready to confirm your booking. From the time you start your search on Hotels.com, the price you see is what you pay. This makes it much easier to compare properties and secure our best deal for your next getaway.
What hotels do travelers recommend in Defiance?
Guests like The Wildwood Hotel.
Can I book refundable accommodations in Defiance?
If you need the flexibility to change your plans to Defiance, most hotels offer refundable* rates you can book. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Defiance be like during my vacation?
July and August are typically the warmest months in Defiance when the average temp is 76°F. January and February are the coldest months when the average temperature is 38°F. May and April are the months with the most rain.
Why should I book my Defiance hotel through Hotels.com?
There are lots of reasons to book your Defiance trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.