Hotels in Greenville

Free cancellation options if plans change
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Where to stay in Greenville?

On a rooftop patio

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Learn more about Greenville

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Frequently asked questions

Can I book refundable hotels in Greenville?
If you need the flexibility to change your travel plans to Greenville, most properties provide refundable* rates you can book. You can see these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
What will the weather in Greenville be like during my trip?
With an average temperature of 77°F during the coldest months, Greenville is a great place to visit any time of year.
Why should I book my Greenville accommodation with Hotels.com?
There are plenty of reasons to book your Greenville travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.