Hotels in Lower Florida Keys

your current months are January, 2025 and February, 2025.
January 2025
February 2025
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Where to stay in Lower Florida Keys?

The Grand Guesthouse
Exterior

The Grand Guesthouse

2.5 star property
9.6 out of 10, Exceptional, (978)
The price is $390
includes taxes & fees
$346 per night
Feb 7 - Feb 8
The Grand Guesthouse
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top neighborhoods in Lower Florida Keys

Audubon House and Tropical Gardens featuring a house

Key West Historic District

Old Town Key West boasts a rich history with 2485 historic buildings, and is home to popular attractions like Ernest Hemingway House and Mallory Square. Enjoy the lively atmosphere in the central business district.

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Key West Historic District

Top landmarks in Lower Florida Keys

Duval Street featuring signage

Duval Street

If you want to give your credit card some exercise, head out to Duval Street in Key West Historic District. Splash some more cash at We Cycle Key West and Mallory Dock.

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Duval Street

Learn more about Lower Florida Keys

Lower Florida Keys is applauded for its cultural attractions such as Ernest Hemingway Home and Museum and Key West Lighthouse and Keeper's Quarters Museum.

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Key West featuring a marina, a coastal town and general coastal views

Frequently asked questions

What hotels do travelers recommend in Lower Florida Keys?
Almond Tree Inn Hotel - Adults Only, The Mermaid & Alligator and LA TE DA Hotel - Adults Only are all accommodations that are popular with guests.
Can I book a refundable hotel in Lower Florida Keys?
If you want the flexibility to change your travel plans to Lower Florida Keys, most hotels provide refundable* bookable rates. You can find these properties by searching our site and using the “fully refundable” filter to narrow down the results.
Which Lower Florida Keys hotels do travelers like for their terrific location?
Our guests rave about the location of these properties: Havana Cabana at Key West, 24 North Hotel Key West and Margaritaville Beach House Key West. For a quiet location, travelers like Southernmost Beach Resort and The Southernmost Inn - Adults Only.
Where should I consider staying in Lower Florida Keys if I want a budget-friendly accommodation?
Hampton Inn Key West FL is an accommodation you might want to consider that’ll save you money.
Where can I stay in Lower Florida Keys if I want a vacation home instead of a hotel?
If you want a good alternative to a hotel, browse our selection of 1720 vacation homes. In addition, there are 191 apartments and 602 condos.
Why should I book my Lower Florida Keys accommodation with Hotels.com?
There are lots of reasons to book your Lower Florida Keys trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.