Hotels in Lower Keys

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Check prices for these dates

Tonight
May 10 - May 11
Tomorrow
May 11 - May 12
Next weekend
May 16 - May 18
In two weeks
May 23 - May 25

Where to stay in Lower Keys?

Looe Key Reef Resort
Boating

Looe Key Reef Resort

2.5 star property
7.4 out of 10, Good, (1003)
$149 nightly
The price is $168
Jun 1 - Jun 2
Total includes taxes and fees
Looe Key Reef Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top neighborhoods in Lower Keys

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Cutthroat Harbor Estates

The Cutthroat Harbor Estates neighborhood offers attractions such as Florida Keys Beaches and Sugarloaf Beach.

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Cutthroat Harbor Estates

Top landmarks in Lower Keys

Bahia Honda State Park

Bahia Honda State Park

Bahia Honda State Park is 5.8 mi (9.3 km) from central Big Pine Key, why not stop by during your stay.

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Bahia Honda State Park

Learn more about Lower Keys

Admired for its parks and waterfront, Lower Keys features attractions such as Florida Keys Beaches and Sugarloaf Beach. Visitors to this relaxing city speak highly of the bars whereas sights include Calusa Beach and Boca Chica Beach.

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Big Pine Key featuring a river or creek, a bay or harbor and general coastal views
A tranquil hotel pool encircled by beautiful arches, enhancing the ambiance for leisure and relaxation.

Summer Getaway Sale

Save 25% or more on select hotels, and earn 50% more rewards on all properties. Book by May 26 and travel by Sep 30, 2025. See terms*
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Frequently asked questions

What accommodations do travelers like in Lower Keys?
Barnacle Bed and Breakfast, Parmer’s Resort and Sunshine Key RV Resort & Marina are all accommodations that are popular with guests.
Can I book a refundable hotel in Lower Keys?
If you need the flexibility to change your travel plans to Lower Keys, most hotels provide refundable* bookable rates. You can see these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
Which Lower Keys hotels do travelers like for their central location?
Our guests love these properties for their good location: Sugar Loaf Lodge and Looe Key Reef Resort.
Where should I consider staying in Lower Keys if I want a reasonably priced accommodation?
Sugar Loaf Lodge and Looe Key Reef Resort are two accommodations you might want to consider that’ll save you money.
Where can I stay in Lower Keys if I want a vacation rental instead of a traditional hotel?
If you want a good alternative to a hotel, browse our selection of 524 vacation homes. You can also consider one of the 52 cottages for your trip.
Why should I book my Lower Keys hotel through Hotels.com?
There are lots of reasons to book your Lower Keys trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

OneKeyCash is not redeemable for cash and can only be used on Hotels.com®, Expedia®, and Vrbo®.

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