Hotels in Eastern Panama

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Check prices for these dates

Tonight
May 12 - May 13
Tomorrow
May 13 - May 14
This weekend
May 16 - May 18
Next weekend
May 23 - May 25

Where to stay in Eastern Panama?

Ordovician Beach Resort
Luxury Suite | Egyptian cotton sheets, premium bedding, pillowtop beds, in-room safe

Ordovician Beach Resort

4.5 star property
10.0 out of 10, Exceptional, (1)
$540 nightly
The price is $594
May 27 - May 28
Total includes taxes and fees
Ordovician Beach Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Eastern Panama

Museum of the Kuna Nation

Museum of the Kuna Nation is 0.3 mi (0.5 km) from central Masargantupo, why not stop by during your stay. If you want to experience more of the culture Masargantupo has to offer, head to Cayos Holandeses.

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Museum of the Kuna Nation

Learn more about Eastern Panama

Eastern Panama is well-known for its attractions such as Cayos Holandeses and Chagres National Park. The city has something for everyone including sights like Darien National Park and Isla Mamey within a tropical setting.

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A tranquil hotel pool encircled by beautiful arches, enhancing the ambiance for leisure and relaxation.

Summer Getaway Sale

Save 25% or more on select hotels, and earn 50% more rewards on all properties. Book by May 26 and travel by Sep 30, 2025. See terms*
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Frequently asked questions

What accommodations do travelers like in Eastern Panama?
Coconut Grove Lodge is a property that our guests really like.
Can I book refundable accommodations in Eastern Panama?
If you want the flexibility to change your plans to Eastern Panama, most hotels provide refundable* rates you can book. You can find these properties by searching our site and using the “fully refundable” filter to narrow down the results.
Which Eastern Panama hotels do travelers like for their terrific location?
Our guests rave about the location of Coconut Grove Lodge.
Where can I stay in Eastern Panama if I'm looking for an affordable accommodation?
A few inexpensive options worth considering are Explora San Blas, Private wood Cabins on San Blas island - private bathroom and Wailidup Hotel.
Where can I stay in Eastern Panama if I want a vacation rental instead of a traditional hotel?
If you’re looking for a good alternative to a hotel, look over our selection of 14 vacation homes. You can also book one of the 16 cabins for your stay.
Why should I book my Eastern Panama hotel with Hotels.com?
There are plenty of reasons to book your Eastern Panama travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

OneKeyCash is not redeemable for cash and can only be used on Hotels.com®, Expedia®, and Vrbo®.

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