Hotels in Central Highlands

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Tonight
May 12 - May 13
Tomorrow
May 13 - May 14
This weekend
May 16 - May 18
Next weekend
May 23 - May 25

Where to stay in Central Highlands?

Hotel Museo Spa Casa Santo Domingo
Fitness studio

Hotel Museo Spa Casa Santo Domingo

4.5 star property
9.2 out of 10, Wonderful, (1007)
$199 nightly
The price is $242
Jun 1 - Jun 2
Total includes taxes and fees
Hotel Museo Spa Casa Santo Domingo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Central Highlands

Showing deals for:May 23 - May 25

Image gallery for Porta Hotel Antigua

Property amenity
VIP Access

Porta Hotel Antigua

4.5 star property
Antigua Guatemala
9.4/10Exceptional (1,001 reviews)
22% off
Price is $544
$223 nightly
$544 total
Total includes taxes and fees
Porta Hotel Antigua

Top neighborhoods in Central Highlands

Okland

Zona 10

Guatemala City's Zona 10 neighborhood is known for its restaurants and bars, and entices visitors with attractions including Oakland Mall and Plaza Fontabella Shopping Center.

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Zona 10

Top landmarks in Central Highlands

Ruins of Old Mayan Monastery destroyed during earthquake in 15th century !

Casa Santo Domingo Museum

If museums are on your list of things to see, you might want to browse the collections at Casa Santo Domingo Museum in Barrio de La Concepción. You can also discover the cathedral and churches in the area. If you want to see more of the museums in Antigua Guatemala, you can easily walk to Antigua Guatemala Colonial Art Museum or Jade Maya Factory and Museum.

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Casa Santo Domingo Museum

Learn more about Central Highlands

Central Highlands is well-known for its ruins and rich culture, featuring attractions such as Biotopo del Quetzal and Grutas Rey Marcos. The city has something for everyone including its museums, cafes, and sights like Central Market and Paseo Cayala.

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Las Victorias National Park which includes rainforest
A tranquil hotel pool encircled by beautiful arches, enhancing the ambiance for leisure and relaxation.

Summer Getaway Sale

Save 25% or more on select hotels, and earn 50% more rewards on all properties. Book by May 26 and travel by Sep 30, 2025. See terms*
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Frequently asked questions

What hotels do travelers like in Central Highlands?
San Rafael Hotel, Las Cruces Boutique Hotel and Hotel Genessis are all accommodations that are popular with guests.
Can I book refundable hotels in Central Highlands?
If you want the flexibility to change your plans to Central Highlands, most accommodations provide refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow the results down.
Which Central Highlands hotels do guests like for their terrific location?
Travelers like these properties for their convenient location: Hotel Museo Spa Casa Santo Domingo, Conquistador Hotel and Conference Center and Adriatika Hotel & Residence.
Where can I stay in Central Highlands if I want a vacation home instead of a hotel?
If you’re looking for a good alternative to a hotel, look over our selection of 179 vacation homes. In addition, there are 166 apartments and 9 condos.
Why should I book my Central Highlands hotel through Hotels.com?
There are plenty of reasons to book your Central Highlands travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

OneKeyCash is not redeemable for cash and can only be used on Hotels.com®, Expedia®, and Vrbo®.

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