Hotels in Central Iowa

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Tonight
May 11 - May 12
Tomorrow
May 12 - May 13
Next weekend
May 16 - May 18
In two weeks
May 23 - May 25

Where to stay in Central Iowa?

Des Lux Hotel
Lobby sitting area

Des Lux Hotel

3.5 star property
9.6 out of 10, Exceptional, (1005)
$189 nightly
The price is $212
May 12 - May 13
Total includes taxes and fees
Des Lux Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Central Iowa, IA

Showing deals for:May 23 - May 25

Image gallery for Comfort Inn & Suites Event Center

Indoor pool

Comfort Inn & Suites Event Center

2.5 star property
Des Moines
8.8/10Excellent (1,006 reviews)
15% off
Price is $331
$148 nightly
$331 total
Total includes taxes and fees
Comfort Inn & Suites Event Center

Top neighborhoods in Central Iowa

State Historical Society of Iowa Museum which includes landscape views, a skyscraper and a city

Downtown Des Moines

Downtown Des Moines boasts corporate campuses, fine dining, and unique retail destinations. Explore the Pappajohn Sculpture Park, and enjoy easy access to DART transit and skywalk connections.

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Downtown Des Moines

Top landmarks in Central Iowa

Iowa State University which includes modern architecture

Iowa State University

If you'd like to get a taste of Ames student life, check out Iowa State University, located 2.1 mi (3.4 km) from central Ames.

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Iowa State University

Learn more about Central Iowa

Central Iowa is applauded for its festivals and live music with such cultural attractions as Stephens Auditorium and Farm House Museum. This family-friendly city has something for everyone including its sports, restaurants, and sights like Haunting at Farrar and Grimes Farm and Conservation Center.

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Iowa State University featuring a lake or waterhole and heritage architecture
A tranquil hotel pool encircled by beautiful arches, enhancing the ambiance for leisure and relaxation.

Summer Getaway Sale

Save 25% or more on select hotels, and earn 50% more rewards on all properties. Book by May 26 and travel by Sep 30, 2025. See terms*
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Frequently asked questions

What hotels do travelers like in Central Iowa?
Des Lux Hotel, Fairfield Inn & Suites Des Moines Altoona and Revel Hotel Des Moines Urbandale, Tapestry Collection by Hilton are all properties that our guests really like.
Can I book a refundable hotel in Central Iowa?
If you want the flexibility to change your travel plans to Central Iowa, most accommodations provide refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
Which Central Iowa hotels do guests like for their terrific location?
Our guests rave about the location of these properties: La Quinta by Wyndham Altoona Des Moines, Embassy Suites Hotel Des Moines Downtown and GrandStay Hotel & Suites.
Where can I stay in Central Iowa if I'm looking for a cheap accommodation?
A few inexpensive options worth considering are La Quinta by Wyndham Altoona Des Moines, Adventureland Inn and GrandStay Hotel & Suites. You can browse more choices on our site, including 56 motels.
Where can I stay in Central Iowa if I want a vacation home instead of a hotel?
If you’re looking for a good alternative to a hotel, browse our selection of 329 vacation homes. In addition, there are 260 apartments and 21 condos.
Why should I book my Central Iowa hotel with Hotels.com?
There are plenty of reasons to book your Central Iowa travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

OneKeyCash is not redeemable for cash and can only be used on Hotels.com®, Expedia®, and Vrbo®.

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