Hotels in Southeast Ohio

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Tonight
May 17 - May 18
Tomorrow
May 18 - May 19
Next weekend
May 23 - May 25
In two weeks
May 30 - Jun 1

Where to stay in Southeast Ohio?

Best Western St. Clairsville Inn & Suites
Lobby

Best Western St. Clairsville Inn & Suites

2.5 star property
9.0 out of 10, Wonderful, (736)
$65 nightly
The price is $74
May 18 - May 19
Total includes taxes and fees
Best Western St. Clairsville Inn & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Southeast Ohio, OH

Showing deals for:May 30 - Jun 1

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Front of property

Granville Inn

3.5 star property
Granville
9.6/10Exceptional (648 reviews)
30% off
Price is $399
$181 nightly
$399 total
Total includes taxes and fees
Granville Inn

Top landmarks in Southeast Ohio

The Athens Lunatic Asylum, was a mental hospital operated in Athens, OH. from 1874 until 1993. The area is now known as The Ridges and is owned by Ohio University.

Ohio University

If you'd like to get a taste of Athens student life, check out Ohio University, located 0.3 mi (0.5 km) from central Athens.

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Ohio University

Learn more about Southeast Ohio

Southeast Ohio is hailed for its university life and festivals while top attractions include Hocking Hills State Park. This family-friendly city has something for everyone including its sports, restaurants, and sights like Wayne National Forest Athens Unit and Burr Oak State Park.

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Wheeling which includes a city, a suspension bridge or treetop walkway and a river or creek
Photo by West Virginia Department of Commerce, Communications and Marketing
Open Photo by West Virginia Department of Commerce, Communications and Marketing
A tranquil hotel pool encircled by beautiful arches, enhancing the ambiance for leisure and relaxation.

Summer Getaway Sale

Save 25% or more on select hotels, and earn 50% more rewards on all properties. Book by May 26 and travel by Sep 30, 2025. See terms*
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Frequently asked questions

What accommodations do travelers like in Southeast Ohio?
The Orchard Bed and Breakfast, TownePlace Suites by Marriott Parkersburg and DogHouse Columbus are all accommodations that are popular with guests.
Can I book a refundable accommodation in Southeast Ohio?
If you want the flexibility to change your plans to Southeast Ohio, most hotels provide refundable* bookable rates. You can see these accommodations by searching our site and using the “fully refundable” filter to narrow the results down.
Which Southeast Ohio hotels do guests like for their central location?
Our guests rave about the location of these properties: Microtel Inn & Suites by Wyndham Cambridge, Executive Suites - Columbus East and Ohio University Inn & Conference Center. For quiet surroundings, guests like Baymont by Wyndham Zanesville and Quality Inn & Suites.
Where should I stay in Southeast Ohio if I want a cheap accommodation?
A few inexpensive options worth considering are Microtel Inn & Suites by Wyndham Cambridge, Executive Suites - Columbus East and DogHouse Columbus. You can browse more choices on our site, including 40 motels.
Where can I stay in Southeast Ohio if I want a vacation home instead of a traditional hotel?
If you want a good alternative to a hotel, review our selection of 404 vacation homes. In addition, there are 65 apartments and 6 condos.
Why should I book my Southeast Ohio accommodation with Hotels.com?
There are plenty of reasons to book your Southeast Ohio travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

OneKeyCash is not redeemable for cash and can only be used on Hotels.com®, Expedia®, and Vrbo®.

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