Nestled in the heart of St. Louis, 21C Museum Hotel St Louis offers a luxurious retreat with an indoor pool, coffee shop/cafe, and gym. Indulge in a massage at the spa or enjoy billiards at the bar while relishing cooked-to-order breakfast options.
Reviews
9.09.0 out of 10
Wonderful
Popular amenities
Pool
Spa
Bar
24/7 front desk
Gym
Parking available
Main amenities (12)
Daily housekeeping
Restaurant and bar/lounge
Indoor pool
Breakfast available
Fitness center
Steam room
Valet parking
Room service
Coffee shop/cafe
Spa services
Business center
Meeting rooms
Feel at home (6)
Premium TV channels
Daily housekeeping
Espresso maker
Blackout drapes/curtains
Pets allowed
Elevator
$156 nightly
The total price is $183
$183 total
Aug 31 - Sep 1
Total includes taxes and fees
Room options
Available filters for rooms
Showing 15 of 15 rooms
Loft, 2 Queen Beds
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout drapes/curtains
Separate bedroom
Private bathroom
Bathrobes
431 sq ft
Sleeps 4
2 Queen Beds
Luxury Suite, 1 King Bed
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout drapes/curtains
Separate bedroom
Separate bathtub and shower
Private bathroom
549 sq ft
Sleeps 2
1 King Bed
View all photos for Room (Bunk Bed)
Room (Bunk Bed)
8.08.0 out of 10
Very good
6 reviews
(6 reviews)
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Private bathroom
Bathrobes
237 sq ft
1 bedroom
Sleeps 2
1 Twin Bunk Bed
Deluxe Room, Accessible (Accessible)
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout drapes/curtains
Separate bedroom
Private bathroom
Bathrobes
269 sq ft
Sleeps 2
1 King Bed
Suite, 1 King Bed (Library)
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout drapes/curtains
Separate bedroom
Private bathroom
Bathrobes
732 sq ft
City view
Sleeps 2
1 King Bed
Suite, 1 King Bed (21C)
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout drapes/curtains
Separate bedroom
Separate bathtub and shower
Private bathroom
1119 sq ft
Sleeps 2
1 King Bed
Deluxe Room, 1 Double Bed, Accessible
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout drapes/curtains
Separate bedroom
Private bathroom
Bathrobes
388 sq ft
Sleeps 4
1 Double Bed
View all photos for Deluxe Room, 1 King Bed
Deluxe Room, 1 King Bed
9.29.2 out of 10
Wonderful
68 reviews
(68 reviews)
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout drapes/curtains
Separate bedroom
Private bathroom
Bathrobes
309 sq ft
Sleeps 2
1 King Bed
Deluxe Suite, 1 Double Bed, Accessible
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout drapes/curtains
Separate bedroom
Private bathroom
Bathrobes
517 sq ft
Sleeps 2
1 Double Bed
View all photos for Deluxe Double Room, 2 Queen Beds
Deluxe Double Room, 2 Queen Beds
8.68.6 out of 10
Excellent
19 reviews
(19 reviews)
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout drapes/curtains
Separate bedroom
Private bathroom
Bathrobes
369 sq ft
Sleeps 4
2 Queen Beds
Deluxe Room, 1 Double Bed, Accessible
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout drapes/curtains
Separate bedroom
Private bathroom
Bathrobes
388 sq ft
Sleeps 4
1 Double Bed
View all photos for Room, 1 King Bed, Corner
Room, 1 King Bed, Corner
8.88.8 out of 10
Excellent
23 reviews
(23 reviews)
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout drapes/curtains
Separate bedroom
Private bathroom
Bathrobes
326 sq ft
City view
Sleeps 2
1 King Bed
View all photos for Suite, 1 King Bed
Suite, 1 King Bed
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout drapes/curtains
Separate bedroom
Private bathroom
Bathrobes
517 sq ft
Sleeps 2
1 King Bed
View all photos for Deluxe Suite, 1 King Bed
Deluxe Suite, 1 King Bed
9.29.2 out of 10
Wonderful
5 reviews
(5 reviews)
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout drapes/curtains
Separate bedroom
Private bathroom
Bathrobes
517 sq ft
Sleeps 2
1 King Bed
View all photos for Luxury Double Room, 2 Queen Beds
St. Louis Lambert Intl. Airport (STL) - 26 min drive
St. Louis, MO (SUS-Spirit of St. Louis) - 32 min drive
St. Louis Gateway Station - 14 min walk
Kirkwood Station - 24 min drive
8th and Pine Station - 13 min walk
Convention Center Station - 16 min walk
Stadium Station - 18 min walk
Restaurants
Budweiser Kiel Club
City Museum Rooftop Cafe - 5 min walk
Medina Grill - 5 min walk
Idol Wolf - 1 min walk
White Knight Diner - 4 min walk
About this property
21C Museum Hotel St Louis
21C Museum Hotel St Louis puts you in a great location, within just a 10-minute walk of City Museum and Enterprise Center. Guests indulge in massages, then grab a bite to eat at the coffee shop/cafe. Other features of this luxurious hotel include an indoor pool, a bar/lounge, and a fitness center. Fellow travelers say great things about the pool and helpful staff. Public transportation is close by: 8th and Pine Station is just 13 minutes by foot.
Languages
English
At a glance
DONE
Hotel size
104 rooms
DONE
Arriving/Leaving
Check-in start time: 4:00 PM; Check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age: 21
Check-out time is 11:00 AM
DONE
Special check-in instructions
Front desk staff will greet guests on arrival at the property
DONE
Required at check-in
Credit card, debit card, or cash deposit required for incidental charges
Government-issued photo ID may be required
Minimum check-in age is 21
DONE
Children
No cribs (infant beds)
DONE
Pets
Pets allowed (dogs only)*
Service animals welcome
WIFI
Internet
Free WiFi in public areas
Free WiFi in rooms
LOCAL_PARKING
Parking
Onsite valet parking (USD 50 per day; includes in/out privileges)
DONE
Other information
Smoke-free property
Property amenities
Food and drink
Cooked-to-order breakfast (surcharge) each morning 6:30 AM–1:00 PM
Guests can pamper themselves by indulging in the onsite spa services. Services include massages.
Fees & policies
Mandatory fees
You'll be asked to pay the following charges by the property at check-in or check-out. Fees may include applicable taxes:
Service fee: USD 5 per accommodation, per stay
Optional extras
Cooked-to-order breakfast is offered for an extra charge of approximately USD 10 to 25 per person
Pets
Service animals exempt from fees
Pets are allowed for an extra charge of USD 100 per accommodation, per stay
Parking
Valet parking costs USD 50 per day with in/out privileges
Pool, spa, & gym (if applicable)
Reservations are required for massage services and can be made by contacting the property before arrival at the number on the booking confirmation
Policies
Guests can rest easy knowing there's a smoke detector and outdoor lighting on site.
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).
This property accepts credit cards. Cash is not accepted.
Credit cards accepted: Visa, Mastercard, American Express
Also known as
21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)
Frequently asked questions
Does 21C Museum Hotel St Louis offer free cancellation for a full refund?
Yes, 21C Museum Hotel St Louis does have fully refundable room rates available to book on our site. If you’ve booked a fully refundable room rate, this can be cancelled up to a few days before check-in depending on the property's cancellation policy. Just make sure to check this property's cancellation policy for the exact terms and conditions.
Is there a pool at 21C Museum Hotel St Louis ?
Yes, there's an indoor pool.
Are pets allowed at 21C Museum Hotel St Louis ?
Yes, dogs are welcome. There's a charge of USD 100 per accommodation, per stay. Service animals are exempt from fees.
Is parking offered on site at 21C Museum Hotel St Louis ?
Yes. Valet parking costs USD 50 per day.
What are the check-in and check-out times at 21C Museum Hotel St Louis ?
Check-in start time: 4:00 PM; Check-in end time: 11:00 AM. Check-out time is 11:00 AM.
Is there an onsite casino at 21C Museum Hotel St Louis ?
No, this hotel doesn't have a casino, but Horseshoe St. Louis Casino (3-min drive) and Casino Queen (4-min drive) are both nearby.
What is there to do at 21C Museum Hotel St Louis and nearby?
21C Museum Hotel St Louis has an indoor pool and a steam room, as well as spa services.
Are there restaurants at or near 21C Museum Hotel St Louis ?
Yes, there's an onsite restaurant.
What's the area around 21C Museum Hotel St Louis like?
21C Museum Hotel St Louis is in Downtown West, a short 12-minute walk from St. Louis Union Station and 18 minutes' walk from Busch Stadium. Travelers love the hotel's prime location.
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21C Museum Hotel St Louis Reviews
Reviews
9.0
Wonderful
All reviews shown are from real guest experiences. Only travelers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
9.2/10
Cleanliness
9.2/10
Staff & service
9.2/10
Amenities
9.4/10
Property conditions & facilities
9.2/10
Eco-friendliness
Popular mentions
Room
Service staff
Art
Bar
Restaurant
Food
Ambience
Amenities
Parking
Car
What guests liked
Breakfast options were delicious and available at the on-site cafe and restaurant. (12 reviews)
From real guest reviews summarized by AI.
Reviews
10/10 Excellent
Aug 16, 2025
Fun place to stay. Museum on the 2nd floor was so much fun.
Patricia
Patricia, 1-night trip
10/10 Excellent
Jun 26, 2025
Great place to stay.
Jeffrey
Jeffrey, 1-night trip
10/10 Excellent
Aug 1, 2025
Great gym and pool.
Frank
Frank, 3-night trip
10/10 Excellent
Jul 19, 2025
It was a great location
rebecca
rebecca, 1-night trip
10/10 Excellent
Aug 7, 2025
Always enjoy staying at this hotel. Staff is always willing to lend a hand. Love the pool, art, and other amenities.
Matthew
Matthew, 2-night trip
10/10 Excellent
Jun 20, 2025
Great stay
Lima Rose
Lima Rose, 1-night trip
10/10 Excellent
Jul 12, 2025
I loved my stay the room was perfect and very comfortable and clean
Shamiyer
Shamiyer, 1-night trip
10/10 Excellent
Jul 18, 2025
This hotel was absolutely beautiful and so unique. The staff was so amazing and friendly, and the rooms were beautiful. We will definitely be repeat guests.
Nicole
Nicole, 3-night trip
10/10 Excellent
Jul 8, 2025
Great place, decor, art, and people
Will
Will, 2-night trip
10/10 Excellent
Jun 30, 2025
The hotel was very clean and easily accessible between restaurant, room, and galleries.
Jessica
Jessica, 1-night trip
8/10 Good
Jun 30, 2025
Beautiful building and the atmosphere was just relaxing and fun
Roger
Roger, 2-night trip
10/10 Excellent
Jul 12, 2025
Museum is fabulous, lobby and room are terrific!
Mike
Mike, 1-night trip
6/10 Okay
Aug 10, 2025
Nice hotel but the bathroom was dirty and the area was a little shady.
Veronica
Veronica, 1-night trip
8/10 Good
Jul 29, 2025
Wonderful hotel. I always enjoying seeking out and finding a 21C. The vibe was inviting and creative. Beautiful works of art. Loved the pool and gym/sauna/steam room area. We will stay again.
Angela
Angela, 1-night trip
10/10 Excellent
Aug 9, 2025
So different and classy
Leslie
Leslie, 1-night trip
10/10 Excellent
Jul 5, 2025
Great value. Great restaurant. Great staff!
Tabitha
Tabitha, 2-night trip
8/10 Good
Jun 29, 2025
Not a great area but a great hotel
kayla
kayla, 1-night trip
10/10 Excellent
Jul 24, 2025
Everything about this hotel was magical! Food is fove star service people rooms. Saunna workout room and it's beautiful!
Julie
Julie, 2-night trip
10/10 Excellent
Jun 10, 2025
very nice hotel felt worth the money
Korie
Korie, 1-night trip
10/10 Excellent
Jul 28, 2025
Loved it! No complaints
Trenicia
Trenicia, 2-night trip
10/10 Excellent
Jul 7, 2025
Thebhotel itself was beautiful akd clean. Parking, and the flooded streets made it miserable to get around directly around the hotel
Nicole
Nicole, 1-night trip
10/10 Excellent
Jul 8, 2025
Excellent service
Julio
Julio, 1-night trip
10/10 Excellent
Jul 22, 2025
Kevin was especially helpful and good to find a fellow LFC supporter !
Rebecca
Rebecca, 2-night trip
8/10 Good
Jul 3, 2025
All that’s needed is access to parking. The paid lot in the rear was cramped. Love the hotel and staff.
Tyson
Tyson, 2-night trip
10/10 Excellent
Jun 17, 2025
The pool and patio area was beautiful. Everything including the staff was 10/10.