In the heart of Jacksonville, Residence Inn By Marriott Jacksonville - Mayo Clinic Area welcomes you with warm hospitality and a free breakfast buffet. Unwind by the poolside bar, stroll through the garden, or take advantage of coworking spaces and concierge services. Helpful staff have left a lasting impression on previous guests.
4905 SAN PABLO ROAD SOUTH, Jacksonville, FL, 32224
What's nearby
Mayo Clinic Florida - 17 min walk - 1.5 km
University of North Florida - 7 min drive - 9.7 km
St. Johns Town Center - 8 min drive - 11.5 km
Jacksonville Beach Pier - 10 min drive - 9.4 km
TPC Sawgrass - 14 min drive - 14.0 km
Getting around
Jacksonville, FL (CRG-Jacksonville Executive at Craig) - 13 min drive
Jacksonville International Airport (JAX) - 30 min drive
St. Augustine, FL (UST-Northeast Florida Regional) - 32 min drive
Daytona Beach Intl. Airport (DAB) - 85 min drive
Restaurants
Culver's #964 - 4 min drive
M Brothers at Mayo - 18 min walk
Starbucks - 4 min drive
Circle K - 10 min walk
Mayo Clinic - Employee Cafeteria - 18 min walk
About this property
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
When you stay at Residence Inn By Marriott Jacksonville - Mayo Clinic Area, you'll be within a 10-minute drive of Mayo Clinic Florida and St. Johns Town Center. After splashing around at the outdoor pool, you can unwind with a drink at the bar/lounge. A poolside bar and a 24-hour fitness center are offered, and in-room conveniences include refrigerators and microwaves. Fellow travelers love the helpful staff.
At a glance
DONE
Hotel size
155 rooms
Arranged over 7 floors
DONE
Arriving/Leaving
Check-in start time: 4:00 PM; Check-in end time: 6:00 AM
Contactless check-in available
Express check-out available
Late check-in subject to availability
Minimum check-in age: 21
Check-out time is 11:00 AM
Contactless check-out available
DONE
Special check-in instructions
Front desk staff will greet guests on arrival at the property
If you are planning to arrive after 11:00 PM please contact the property in advance using the information on the booking confirmation
DONE
Required at check-in
Credit card, debit card, or cash deposit required for incidental charges
Government-issued photo ID may be required
Minimum check-in age is 21
DONE
Children
No cribs (infant beds)
DONE
Pets
Pets allowed (dogs and cats only, 2 total, up to 40 lbs per pet)*
Service animals welcome
Restrictions apply*
WIFI
Internet
Free WiFi in public areas
Free WiFi in rooms
LOCAL_PARKING
Parking
Free uncovered onsite self parking
Wheelchair-accessible parking and van parking on site
DONE
Other information
Smoke-free property
Property amenities
Food and drink
Free buffet breakfast 6:30 AM–9:00 AM on weekdays and 7:00 AM–9:30 AM on weekends
Bar/lounge
Poolside bar
Coffee/tea in a common area
Barbecue grills
Water dispenser
Traveling with children
Grocery/convenience store
Working away
24-hour business center
2 meeting rooms
Computer station
Coworking spaces
Conference space (2678 square feet)
Services
24-hour front desk
Concierge services
Dry cleaning/laundry services
Free grocery shopping service
Free newspapers in lobby
Luggage storage
Wedding services
Multilingual staff
Pool loungers
Facilities
1 building/tower
Built in 2020
Safe-deposit box at front desk
Garden
Picnic area
Fireplace in lobby
Television in common areas
Communal living room
24-hour fitness center
An outdoor pool
Vegan dining options
Vegetarian dining options
Double-glazed windows
At least 80% lighting from LEDs
Comprehensive food waste policy
Comprehensive recycling policy
No plastic coffee stirrers
Banquet hall
Traditional architecture
Accessibility
Braille/raised signage
Elevator
Wheelchair accessible
Wheelchair-accessible path of travel
Wheelchair-accessible parking
Assistive listening devices available
Wheelchair-accessible public washroom
Wheelchair-accessible concierge desk
Wheelchair-accessible van parking
Wheelchair-accessible path to elevator
Wheelchair-accessible registration desk
Wheelchair-accessible pool
Wheelchair-accessible fitness center
Wheelchair-accessible business center
Wheelchair-accessible restaurant
Wheelchair-accessible lounge
Visual alarms in hallways
Handrails in stairways
Hand-held showerheads
Closed captioned TV
Raised toilet seat
Lowered electrical outlets in bathroom
Lowered peephole/view port in door
Lowered locks/deadbolt
Low-height counter/sink
Low-height bed
Height-adjustable showerhead
Grab bar near toilet
Bathroom emergency pull cord
Accessible bathtub
Vibrating pillow alarm
Lever door handles
Wheelchair-width doorways
Phone accessibility kit
Well-lit path to entrance
Stair-free path to entrance
Pool hoist on site
Room amenities
Be entertained
55-inch Smart TV
Premium cable channels
Netflix
Streaming services
Home comfort
Air conditioning and heating
Coffee/tea maker
Iron/ironing board
Sleep well
Blackout drapes/curtains
Bed sheets provided
What to enjoy
Separate dining area
Separate sitting area
Freshen up
Private bathroom
Bathtub or shower
Free toiletries
Hair dryer
Towels
Toilet paper
Stay connected
Desk
Free WiFi
Phone
Food and drink
Refrigerator
Microwave
Kitchen
Stovetop
Toaster
Cookware, dishes, and utensils
Dishwasher
More
Daily housekeeping
In-room safe (laptop compatible)
Connecting/adjoining rooms available
Energy-saving switches
LED light bulbs
Recycling
Water-efficient showers only
Mobile key entry
Fees & policies
Refundable deposits
Deposit: USD 125 per accommodation, per stay
Pets
Service animals exempt from fees
Pets are allowed for an extra charge of USD 150 per accommodation, per stay
Policies
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.
Only registered guests are allowed in the guestrooms.
Guests can rest easy knowing there's a carbon monoxide detector, a fire extinguisher, a smoke detector, and window guards on site.
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).
This property accepts credit cards. Cash is not accepted.
Credit cards accepted: Visa, Mastercard, American Express, Discover, Diners Club
Cashless transactions are available.
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott).
Also known as
Residence INN BY Marriott Jacksonville
Residence Inn by Marriott Jacksonville East
Residence Inn Jacksonville Mayo Clinic Area
Residence Inn By Marriott Jacksonville - Mayo Clinic Area Hotel
Frequently asked questions
Does Residence Inn By Marriott Jacksonville - Mayo Clinic Area offer free cancellation for a full refund?
Yes, Residence Inn By Marriott Jacksonville - Mayo Clinic Area does have fully refundable room rates available to book on our site. If you’ve booked a fully refundable room rate, this can be cancelled up to a few days before check-in depending on the property's cancellation policy. Just make sure to check this property's cancellation policy for the exact terms and conditions.
Is there a pool at Residence Inn By Marriott Jacksonville - Mayo Clinic Area?
Yes, there's an outdoor pool.
Are pets allowed at Residence Inn By Marriott Jacksonville - Mayo Clinic Area?
Yes, cats and dogs are welcome, with a limit of 2 total and maximum weight of 40 lbs per pet. There's a charge of USD 150 per accommodation, per stay. Service animals are exempt from fees. Some restrictions may apply, so please contact the property for more details.
Is parking offered on site at Residence Inn By Marriott Jacksonville - Mayo Clinic Area?
Yes, there's free self parking.
What are the check-in and check-out times at Residence Inn By Marriott Jacksonville - Mayo Clinic Area?
Check-in start time: 4:00 PM; Check-in end time: 6:00 AM. Check-out time is 11:00 AM. Express check-out and contactless check-in and check-out are available.
What is there to do at Residence Inn By Marriott Jacksonville - Mayo Clinic Area and nearby?
Residence Inn By Marriott Jacksonville - Mayo Clinic Area has an outdoor pool and a 24-hour fitness center, as well as a picnic area and a garden.
Does Residence Inn By Marriott Jacksonville - Mayo Clinic Area have self-catered rooms fitted with kitchens or kitchenettes?
Yes, a kitchen is available in every room, and also includes a coffee maker, a toaster, and cookware.
What's the area around Residence Inn By Marriott Jacksonville - Mayo Clinic Area like?
Residence Inn By Marriott Jacksonville - Mayo Clinic Area is a short 18-minute walk from Mayo Clinic Florida and 18 minutes' walk from Harbor City Municipal Golf Course.
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Residence Inn By Marriott Jacksonville - Mayo Clinic Area Reviews
Reviews
9.4
Exceptional
All reviews shown are from real guest experiences. Only travelers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
9.6/10
Cleanliness
9.6/10
Staff & service
9.0/10
Amenities
9.6/10
Property conditions & facilities
9.4/10
Eco-friendliness
Popular mentions
Room
Service staff
Location
Breakfast
Shuttle
Kitchen
Amenities
Family friendly
Bed
Food
What guests liked
The complimentary breakfast was delicious and offered a great variety of options. (15 reviews)
The pool was beautiful and looked inviting, although one guest was unable to use it. (4 reviews)
From real guest reviews summarized by AI.
Reviews
10/10 Exceptional
Oct 4, 2025
Yes, everything was great
Curtis
Curtis, 7-night trip
10/10 Exceptional
Jun 20, 2025
The place was clean and staff was wonderful. Will be staying again!
Carrie
Carrie, 1-night trip
10/10 Exceptional
May 10, 2025
Excellent accommodations!
Carolyn
Carolyn, 1-night trip
10/10 Exceptional
Aug 14, 2025
Terrific Stay 10/10
I had an amazing stay. The staff was friendly, the room was spotless. All the attractions were minutes away. The hotel felt like home away from home. Highly recommended. I will be back.
Tyeisha
Tyeisha, 2-night trip
10/10 Exceptional
Jun 8, 2025
great stafff comfortable clean room and amenities
Nadine
Nadine, 2-night trip
10/10 Exceptional
Jul 7, 2025
Very nice. About 3.5 miles from the beach. Breakfast was amazing especially loved their
coffee.
SHERICE
SHERICE, 2-night trip
10/10 Exceptional
Jul 3, 2025
Excellence in Hospitality
Mayo Clinic appointment; staff was professional in assisting with appointments vs hotel needs.
Stephen
Stephen, 1-night trip
10/10 Exceptional
Jun 27, 2025
Super happy!!! 2nd time staying here ! Satisfied 2nd time around ! Will be our stay every year we visit Jacksonville!
brenda
brenda, 2-night trip
10/10 Exceptional
Apr 24, 2025
Great Stay!
This is a wonderful place to stay. It offers all of the services that you need. It is in a beautiful setting with great amenities.
Patricia
Patricia, 2-night trip
10/10 Exceptional
May 25, 2025
Visiting Family
It was newer than expected facility and quite nice we had to swim in the pool easy in easy app great parking and the breakfast was exceptional we will be staying there again as we visit family in Jacksonville beach.
Craig
Craig, 2-night trip
10/10 Exceptional
Jul 7, 2025
Loved very
Leah
Leah, 2-night trip
10/10 Exceptional
Feb 18, 2025
Definitely will be staying here anytime we are in
stayed here for a mayo clinic appointment everything was amazing from the time of check-in to check-out.
Patricia
Patricia, 3-night trip
8/10 Very good
Dec 6, 2024
Was perfect place to stay on my visit to Mayo.
Gerard
Gerard, 2-night trip
10/10 Exceptional
May 30, 2025
Clean and friendly. Easy access to Mato and highway
Joan
Joan, 1-night trip
10/10 Exceptional
Jun 27, 2025
Excellent Staff. Cleanliness.
Rishie
Rishie, 1-night trip
10/10 Exceptional
Dec 30, 2024
Very nice hotel !!
Jean-Sebastien
Jean-Sebastien, 1-night trip
10/10 Exceptional
Feb 15, 2025
Absolutely enjoyed our stay. Room was really clean and very nice. Will definitely stay every time we come.
Devon
Devon, 1-night trip
10/10 Exceptional
Apr 26, 2025
It’s very clean and roomy place . And it’s pretty quiet. Breakfast was very good and fresh. Could go back again and recommend to family and friends
Emmaruth
Emmaruth, 1-night trip
8/10 Very good
Apr 11, 2025
Quiet and comfortable
Patrick
Patrick, 3-night trip
8/10 Very good
Jun 29, 2025
Good
Edgar
Edgar, 2-night trip
10/10 Exceptional
Feb 7, 2025
Quiet,clean and convenient to Mayo Clinic!
Jane
Jane, 1-night trip
10/10 Exceptional
Apr 7, 2025
Great Stay
This hotel was better than expected. Studio suite had everything needed for an extended stay including a full size cridhe, dishwasher cookware, dishes.Room was clean and comfortable. Staff were friendly and complimentary breakfast was good with options.
Andrea
Andrea, 2-night trip
10/10 Exceptional
Aug 22, 2024
Always a nice stay.
MJ
MJ, 1-night trip
10/10 Exceptional
May 19, 2025
Nice clean rooms. Smells good and takes great care of the property. No sore eye! This is a home away from home.