Hotels in Santiago Este

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Check prices for these dates

Tonight
May 11 - May 12
Tomorrow
May 12 - May 13
Next weekend
May 16 - May 18
In two weeks
May 23 - May 25

Where to stay in Santiago Este?

Hotel Mykonos Panama
3 outdoor pools, free cabanas, pool umbrellas

Hotel Mykonos Panama

3.5 star property
8.8 out of 10, Excellent, (510)
$81 nightly
The price is $90
May 12 - May 13
Total includes taxes and fees
Hotel Mykonos Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santiago Este

The region around Santiago Este is home to attractions such as Museum of Salt and Sugar and Los Pozos Termales.

See all hotels in Santiago Este
A tranquil hotel pool encircled by beautiful arches, enhancing the ambiance for leisure and relaxation.

Summer Getaway Sale

Save 25% or more on select hotels, and earn 50% more rewards on all properties. Book by May 26 and travel by Sep 30, 2025. See terms*
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Frequently asked questions

What accommodations do travelers like in Santiago Este?
Guests like AMAZING TINY HOUSE casa 8.
Can I book refundable accommodations in Santiago Este?
If you want the flexibility to change your plans to Santiago Este, most properties offer refundable* bookable rates. You can see these properties by searching our site and using the “fully refundable” filter to narrow the results down.
What will the weather in Santiago Este be like during my trip?
With an average temperature of 77°F during the coldest months, Santiago Este is a great place to visit any time of year.
Why should I book my Santiago Este accommodation with Hotels.com?
There are plenty of reasons to book your Santiago Este travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

OneKeyCash is not redeemable for cash and can only be used on Hotels.com®, Expedia®, and Vrbo®.

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