Photo by Jennifer Radman

Hotels in Des Peres

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Check prices for these dates

Tonight
Jul 4 - Jul 5
Tomorrow
Jul 5 - Jul 6
This weekend
Jul 4 - Jul 6
Next weekend
Jul 11 - Jul 13

Where to stay in Des Peres?

Best Western St. Louis-Kirkwood Route 66
Lobby

Best Western St. Louis-Kirkwood Route 66

3.5 star property
8.6 out of 10, Excellent, (1190)
$108 nightly
The price is $126
Aug 3 - Aug 4
Total includes taxes and fees
Best Western St. Louis-Kirkwood Route 66
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Des Peres

Museum of Transportation

Museum of Transportation

Museum of Transportation is 2.5 mi (4 km) from central Des Peres, why not stop by during your stay. If you want to experience more of the culture Des Peres has to offer, head to Magic House - St. Louis Children's Museum, Castlewood State Park, and Missouri Baptist Medical Center.

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Museum of Transportation

Sugar Creek Park

Sugar Creek Park is worth a visit, located 1.8 mi (2.9 km) from central Des Peres. Our travelers also like the museums in the area— your cultural tour starts here.

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Sugar Creek Park

Learn more about Des Peres

Busch Stadium, St. Louis Zoo, and St. Louis Union Station are some of the top attractions around Des Peres.

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Museum of Transportation featuring interior views and signage

Check out the Des Peres hotels guests love right now

21C Museum Hotel St Louis

21C Museum Hotel St Louis

10/10 Excellent
"It was a beautiful hotel. Love the scenery. Love how the remodeled the building. It was nostalgic for me. I use to play in that building with my dad as a child. The staff was nice. I did not like the parking. "
Jammetta 1-night trip
Posted 21 hours ago
21C Museum Hotel St Louis

Frequently asked questions

What hotels do travelers like in Des Peres?
Guests like Clayton Plaza Hotel & Extended Stay, Moonrise Hotel and Best Western St. Louis-Kirkwood Route 66.
Can I book refundable hotels in Des Peres?
If you need the flexibility to change your plans to Des Peres, most accommodations offer refundable* rates you can book. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Des Peres be like during my trip?
The warmest months in Des Peres are usually July and August with an average temp of 76°F. January and February are the chilliest months when the average temp is 37°F. The rainiest months are May and April.
Why should I book my Des Peres accommodation with Hotels.com?
There are plenty of reasons to book your Des Peres travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Find out more about Des Peres

Find out more about Des Peres

If you're looking to discover somewhere new, look no further than Des Peres. Whether you're planning to stay for a night or for the week, the area around Des Peres has accommodations to fit every need. Search for hotels in Des Peres with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Des Peres hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Des Peres hotel deals are here with our lowest price guarantee.