If you're looking to discover somewhere new, look no further than Caño Negro. Whether you're planning to stay for a night or for the week, the area around Caño Negro has accommodations to fit every need. Search for hotels in Caño Negro with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Caño Negro hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Caño Negro hotel deals are here with our lowest price guarantee.
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Hotels in Caño Negro
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Where to stay in Caño Negro?

Natural Lodge Caño Negro
Natural Lodge Caño Negro
7.8 out of 10, Good, (28)
$236 nightly
The price is $267
May 17 - May 18
Total includes taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Caño Negro
The region around Caño Negro is home to attractions such as Cano Negro National Wildlife Refuge and Medio Queso Wetlands.

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*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.
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