Hotels in Colón

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Check prices for these dates

Tonight
May 15 - May 16
Tomorrow
May 16 - May 17
This weekend
May 16 - May 18
Next weekend
May 23 - May 25

Where to stay in Colón?

Learn more about Colón

You can explore the area's natural beauty at Malpelo Fauna and Flora Sanctuary during your stay.

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A tranquil hotel pool encircled by beautiful arches, enhancing the ambiance for leisure and relaxation.

Summer Getaway Sale

Save 25% or more on select hotels, and earn 50% more rewards on all properties. Book by May 26 and travel by Sep 30, 2025. See terms*
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Frequently asked questions

What accommodations do travelers like in Colón?
Guests like Hotel San Blass.
Can I book a refundable hotel in Colón?
If you need the flexibility to change your plans to Colón, most hotels provide refundable* bookable rates. You can see these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
What will the weather in Colón be like during my vacation?
September and August are typically the warmest months in Colón when the average temp is 65°F. January and December are the coldest months when the average temperature is 64°F. April and May are the months with the most rain.
Why should I book my Colón hotel with Hotels.com?
There are lots of reasons to book your Colón trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

OneKeyCash is not redeemable for cash and can only be used on Hotels.com®, Expedia®, and Vrbo®.

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