Hotels in Medicine Lake

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Tonight
May 16 - May 17
Tomorrow
May 17 - May 18
This weekend
May 16 - May 18
Next weekend
May 23 - May 25

Where to stay in Medicine Lake?

Top landmarks in Medicine Lake

Medicine Lake National Wildlife Refuge

Medicine Lake National Wildlife Refuge is 2.8 mi (4.5 km) from central Medicine Lake, why not stop by during your stay.

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Medicine Lake National Wildlife Refuge

Learn more about Medicine Lake

The region around Medicine Lake is home to attractions such as Medicine Lake National Wildlife Refuge and Big Island.

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A tranquil hotel pool encircled by beautiful arches, enhancing the ambiance for leisure and relaxation.

Summer Getaway Sale

Save 25% or more on select hotels, and earn 50% more rewards on all properties. Book by May 26 and travel by Sep 30, 2025. See terms*
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Frequently asked questions

What accommodations do travelers recommend in Medicine Lake?
Guests like Newly remodeled home minutes from Medicine Lake NWR..
Can I book a refundable hotel in Medicine Lake?
If you need the flexibility to change your plans to Medicine Lake, most properties provide refundable* bookable rates. You can see these properties by searching our site and using the “fully refundable” filter to narrow down the results.
What will the weather in Medicine Lake be like during my vacation?
July and August are typically the warmest months in Medicine Lake when the average temp is 67°F. February and January are the coldest months when the average temperature is 18°F. June and May are the months with the most rain.
Why should I book my Medicine Lake accommodation with Hotels.com?
There are lots of reasons to book your Medicine Lake trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

OneKeyCash is not redeemable for cash and can only be used on Hotels.com®, Expedia®, and Vrbo®.

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