Hotels in Saint Charles

Free cancellation options if plans change
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Check prices for these dates

Tonight
Feb 12 - Feb 13
Tomorrow
Feb 13 - Feb 14
This weekend
Feb 14 - Feb 16
Next weekend
Feb 21 - Feb 23

Where to stay in Saint Charles?

On a rooftop patio

Use code VALENPOWER for an extra 10% off your next getaway

One Key™ members get an extra 10% off hotels, book by Feb 17, travel between Feb 6 through Aug 31 (US customers only).*T&Cs apply

Learn more about Saint Charles

The region around Saint Charles is home to attractions such as White River and DeWitt Commercial Historic District.

See all hotels in Saint Charles

Frequently asked questions

What hotels do travelers like in Saint Charles?
Guests like Outdoors!!.
Can I book a refundable hotel in Saint Charles?
If you need the flexibility to change your plans to Saint Charles, most properties provide refundable* bookable rates. You can see these properties by searching our site and using the “fully refundable” filter to narrow the results down.
What will the weather in Saint Charles be like during my trip?
July and August are typically the warmest months in Saint Charles when the average temp is 79°F. January and February are the coldest months when the average temperature is 47°F. April and March are the months with the most rain.
Why should I book my Saint Charles hotel with Hotels.com?
There are lots of reasons to book your Saint Charles trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.